Health Tools. Ondansetron Zofran. Reviewed: November 16, You should not use ondansetron if: you are also using apomorphine Apokyn ; or you are allergic to ondansetron or similar medicines dolasetron, granisetron, palonosetron.
To make sure ondansetron is safe for you, tell your doctor if you have: liver disease; an electrolyte imbalance such as low levels of potassium or magnesium in your blood ; congestive heart failure, slow heartbeats; a personal or family history of long QT syndrome; or a blockage in your digestive tract stomach or intestines.
Side Effects. Side Effects What are the side effects of Ondansetron Zofran? Call your doctor at once if you have: severe constipation, stomach pain, or bloating; headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; fast or pounding heartbeats; jaundice yellowing of the skin or eyes ; blurred vision or temporary vision loss lasting from only a few minutes to several hours ; high levels of serotonin in the body --agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.
Common side effects may include: diarrhea or constipation; headache; drowsiness; or tired feeling. Based on FDA pregnancy categories. Interactions What drugs and food should I avoid while taking Ondansetron Zofran?
Ondansetron can be taken with or without food. Take the ondansetron regular tablet with a full glass of water. To take the orally disintegrating tablet Zofran ODT :. To use ondansetron oral soluble film strip Zuplenz :. What should I do if I missed a dose of Ondansetron Zofran?
If you think you or someone else may have overdosed on: Ondansetron Zofran , call your doctor or the Poison Control center. If someone collapses or isn't breathing after taking Ondansetron Zofran , call What to Expect Ondansetron usually starts to work within about 30 minutes. Its effects can last 8 to 12 hours. Ondansetron orally disintegrating tablets may contain phenylalanine.
Tell your doctor if you have phenylketonuria PKU. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. The first dose of ondansetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment.
Follow your doctor's dosing instructions very carefully. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture, heat, and light.
Store liquid medicine in an upright position. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. Ondansetron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Get emergency medical help if you have signs of an allergic reaction: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Ondansetron can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron. Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal. Tell your doctor if you also use:. This list is not complete and many other drugs can interact with ondansetron.
This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. It will melt in a few seconds and then your child should swallow. What to do for a missed dose.
What should you do if your child misses a dose of ondansetron? If your child misses a dose of ondansetron: Give it as soon as you remember, if your child is feeling sick. Skip the missed dose if it is almost time for the next dose and your child feels well. Wait at least 4 hours after ondansetron before you give the next dose, if you gave the dose late. For example, suppose your child's dose times are 8 a. If you miss the 8 a. Then go back to the regular dose time.
Give your child only one dose at a time. However, if your child vomits throws up less than 30 minutes after you gave a dose, you may give another dose. Side effects. What are the possible side effects of ondansetron? Call your child's contact nurse or doctor if your child has any of these signs or symptoms and they do not go away or they bother your child: headache dizziness constipation diarrhea loose, watery stools dry mouth feeling of warmth or flushing red face, body Call your child's doctor or nurse as soon as possible, during office hours, if your child has any of these signs: rash, hives raised, red, itchy areas on the skin or itching Most of the following side effects are not common, but they may be a sign of a serious problem.
Call your child's doctor right away or take your child to the Emergency Department if your child has any of these side effects: swelling of eyelids or face difficulty breathing chest pain, heart pounding or racing rapid or irregular heart rate , feeling faint. Safety measures. What safety measures should you take when your child is using ondansetron?
It is important that you tell your doctor and pharmacist if your child takes any other medications, including: antiepileptic medicines, including carbamazepine and phenytoin heart medicines, including amiodarone and sotalol medicines used to treat mood disorders, including citalopram and sertraline antibiotics, such as clarithromycin antifungals, such as fluconazole or voriconazole cyclosporine , tacrolimus cisapride , domperidone Check with your child's doctor or pharmacist before giving your child any other medicines prescription, non-prescription, herbal or natural products.
Other important information. What other important information should you know about ondansetron? Other medicines may not work well with ondansetron. Check with your child's doctor or pharmacist before you give your child any other medicines, even medicines that you can buy without a doctor's order prescription.
If you do not think that ondansetron is working for your child, talk to your child's doctor. You may be asked to give a dose of ondansetron to your child before going to clinic. Give your child ondansetron 30 to 60 minutes before they are given chemotherapy. Disintegrating tablets contain aspartame. Children with phenylketonuria often called PKU should not receive aspartame.
Disintegrating tablets contain gelatin. Some diets do not allow gelatin. If your child takes ODT: Tear the package along the dotted holes perforations to make 1 dose.
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